New Treatment Guidelines for Ovarian Cancer in 2022

Several ovarian cancer therapies are available, and your oncologist or surgeon will go through each with you to determine which one is best for you. Chemotherapy and surgery are among the therapies available. Surgery allows your oncologist to remove as much cancer as possible, while chemotherapy kills any cancer cells that remain after surgery. Chemotherapy will also aid in treating any cancer that has spread following surgery. Depending on the types of cancer, surgery to remove the fallopian tubes and ovaries may be required.


Surgical therapy may include the removal of your ovaries, fallopian tubes, and uterus. In addition, your omentum, a fatty tissue surrounding your intestines, may need to be removed. Your surgeon will try to remove as much cancer as possible, but if cancer has spread, you may also need to remove other portions of your body.


Ovarian cancer therapies that can lessen symptoms are available after surgery and chemotherapy. Chemotherapy and hormone therapy may be used as therapies. Depending on your specific problem, you may also be offered hormonal medications such as tamoxifen, letrozole, or anastrozole. Even if you do not require chemotherapy, you must discuss your treatment alternatives with your healthcare specialists. An effective treatment strategy can assist you in dealing with the sickness.


The majority of ovarian tumors begin in the ovaries' outer lining. Most women are not diagnosed until the illness has progressed to other regions of their bodies. This makes it critical to get diagnosed as soon as possible. Only 20% of women are now detected with the disease before it extends beyond the ovaries.


Another treatment option for ovarian cancer is radiation therapy. This kind of therapy entails entering the circulation and destroying cancer cells. While it is not widely used to treat ovarian cancer, it is occasionally used with chemotherapy. This treatment is incredibly successful if cancer has gone beyond the ovaries. Furthermore, tailored medications that target specific tumor cells in the body have been produced.


Avastin is a targeted therapy that targets the aberrant genetic alterations that cause cancer. These medications inhibit the genes that cause cancer to develop. They can also aid in the prevention of the formation of new blood vessels, which starves the malignancy. Other targeted therapies may also be beneficial in some cases. Combining two or more ICIs may also be advantageous.


Researchers are also searching for new effective treatments for ovarian cancer. Developing tailored antibodies that target a particular gene is one possible method. These drugs target HER2, or the Human Epidermal Growth Factor Receptor 2. Ovarian cancer therapies can help people enhance their quality of life. TH1902 (Sortilin) is one of these medicines that target the ER and vascular tissue. It is an experimental medicine, although its development is still in its early phases.


Surgery is another effective therapy for ovarian cancer. Therefore, ovarian cancer is often treated with chemotherapy and surgery. Typically, platinum-based carboplatin and taxane-based paclitaxel are used as first-line chemotherapy for ovarian cancer. For 80% of patients, it typically leads to a complete response. This treatment may also include a PARP inhibitor maintenance regimen, which has shown promise in postponing recurrence in particular women.


Ovarian cancer treatments may include immunotherapy in addition to chemotherapy. Proteins and immunomodulators are used in this therapy to enhance the immune system. Other therapies include cancer vaccinations and viruses engineered to attack cancer cells. Immunotherapy is not a typical treatment for ovarian cancer, although it may be an option for patients with advanced illnesses. If you're interested in this treatment, speak with your oncologist to discover if you're a candidate for a clinical trial.

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